Home  |  Find Your Chapter  |  Get Involved  |  Advocacy/Government Affairs  |  Press Room  |  About The Society  |  Library
ABOUT MS LIVING WITH MS TREATMENTS RESEARCH HEADLINES SPECIAL EVENTS For Professionals
National Multiple Sclerosis Society  
Join The Movement
Donate Search Contact Us
 

Research

 

Current Funded Research > New Jersey

 

Nancy D. Chiaravalloti, PhD

Kessler Medical Rehabilitation
Research and Education Corp.

West Orange, NJ

Region: Greater North Jersey Chapter

Award: Research Grant

Term/Amount: 4/1/04-3/31/08; $428,372

 

“Working memory in MS: Using fMRI to identify the deficit Correlating memory difficulties with brain activity to understand how to overcome such difficulties in MS.

 

Many people with MS report difficulties with attention, concentration, and memory. Nancy D. Chiaravalloti, PhD, and colleagues have shown that deficits in “working memory” may be the source of some cognitive difficulties. Working memory refers to the ability to hold and manipulate information in the brain (e.g., add numbers without writing them down).

 

Now, Dr. Chiaravalloti's team is seeking to identify more precisely how working memory may be impaired in some people with MS. Working memory involves two processes: holding information in the brain and manipulating this information.

 

The investigation involves 20 people with MS who have an impairment in working memory; 20 people with MS without working memory impairment; and 20 people without MS. Participants are undergoing neuropsychological assessment and functional magnetic resonance imaging (fMRI). fMRI allows researchers to take active images of the brain while it is performing working memory tasks that require either maintaining or manipulating information. The patterns of activation between the groups will be compared to identify specific sites in the brain responsible for working memory deficits in MS.

Results of this study will help us to better understand the source of working memory deficits in people with MS, and improve our ability to track changes in working memory, especially as a result of treatment.

 

FAQsGlossary of MS Terms  


ChatMessage Boards
Email This PagePrint This Page
Home | MS Learn Online Webcasts | Spotlight Series | Información en español | Site Map

National Multiple Sclerosis Society | 1-800-344-4867

© 2007 The National Multiple Sclerosis Society. All rights reserved. Legal Notice/Privacy Policy | Powered by Convio